ET is a chronic disease that may transform to MF

Essential thrombocythemia (ET) is a myeloproliferative neoplasm (MPN) characterized by thrombocytosis with bone marrow megakaryocytic hyperplasia and a tendency to develop thrombotic and hemorrhagic complications.1-3

In some patients, ET may transform to myelofibrosis (MF), called post-ET MF.4 ET can also transform to secondary acute myelogenous leukemia in a small minority of patients.5

References: 1. Cervantes F. Hematology Am Soc Hematol Educ Program. 2011;2011:215-221. 2. Tefferi A, Barbui T. Leukemia. 2013;27(8):1617-1620. 3. Wolanskyj AP, Schwager SM, McClure RF, Larson DR, Tefferi A. Mayo Clin Proc. 2006;81(2):159-166. 4. Verstovsek S. Clin Cancer Res. 2010;16(7):1988-1996. 5. Abdel-Wahab O, Manshouri T, Patel J, et al. Cancer Res. 2010;70(2):447-452.

Get key information for critical ET topics

Risk

Find out about the long-term prognosis for patients with ET and see which variables are associated with shortened survival.

Diagnosis

Review the most common ET signs and symptoms and discover why diagnosis may be difficult.